This study evaluates the antimycobacterial potential of novel "mutual" bioactive amides, combining pyridine-4-carbohydrazide (isoniazid, INH) with various antimicrobial agents (sulphonamides,...

Three molecular adducts of the antituberculosis drug isoniazid (INH) are synthesized with γ-resorcylic acid ( RA), phloroglucinol (PG), and gallic acid (GA). The new solid phases are preliminarily characterized by γ the thermal analysis (DSC/TGA) and powder X-ray diffraction.

We showed that the two-time deprotonated gallic acid species forms the coordination compound with Fe (II) ions in a 1:1 molar ratio. To gain better insight into the process, the coordination compound formation was also studied using various DFT …

Sep 18, 2024 · Later, the discovery of isoniazid (INH) initiated a combined triple therapy evaluation of INH, STM and PAS. This study proved the efficacy of this combination involving a treatment of 24 months (Capon, 1954).

Gallic acid mainly exists in Galla Chinensis, showing free radical scavenging, antioxidant, antitumor, and anti-inflammatory activities. Sanjay et al. reported the protective effect of gallic acid in INH and RFP-induced liver injury in Wistar rats ( Sanjay et al., 2021 ).

We investigated how the properties of these gels were affected at varying pH, by the formation of complexes between the polymer network of the gels and Fe 3+ ions (which form stable complexes with gallic acid, exhibiting 1:1, 1:2, or 1:3 stoichiometry, depending on pH).

In GANA (Gallic acid-Nicotinic acid) hydrate reveals two distinct hydrogen bonding motifs between gallic acid and nicotinic acid. In one orientation, the carbonyl oxygen of nicotinic acid participates in hydrogen bonding, while in the other, the nitrogen atom acts as the hydrogen bond acceptor.

Dec 5, 2019 · In the present study, the properties of MNZ were optimized through a cocrystallization strategy. A cocrystal of MNZ is prepared using gallic acid (GA) as cocrystal former.

Nov 26, 2024 · Dietary tannins can affect rumen microbiota and enteric fermentation to mitigate methane emissions, although such effects have not yet been fully elucidated. We tested two subunits of hydrolyzable tannins named gallic acid (GA) and ellagic acid (EA), alone (75 mg/g DM each) or combined (150 mg/g DM …

Gallic Acid | C7H6O5 | CID 370 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.