Langerhans cells derive from primitive erythro-myeloid progenitors that arise in the yolk sac outside the embryo in the first trimester of pregnancy, and under normal circumstances persist …

Apr 26, 2021 · Langerhans cells are members of the dendritic cell family and function as antigen-presenting cells (APCs) in the skin. They capture any pathogens they find roaming the …

Langerhans cells (LCs) are a specialized subset of dendritic cells (DCs) that populate the epidermal layer of the skin. Langerin is a lectin that serves as a valuable marker for LCs in …

Jan 28, 2025 · Langerhans cells are a specialized subset of dendritic cells located primarily in the epidermis of the skin. Discovered by Paul Langerhans in 1868, these cells play a crucial role in …

Langerhans cells (LCs) are antigen-presenting dendritic cells (DCs) that reside in epithelia. The best studied example is the LC of the epidermis. By electron microscopy, their identifying …

Langerhans cells (LCs) originate pre-natally and may endure throughout life, independently of bone marrow derived precursors. Fate mapping experiments have recently resolved the …

Langerhans cells (LCs) were first described by Paul Langerhans, in 1868, as dendritically shaped cells, which were located in the squamous epithelia of epidermis. Later on, these cells were …

Jan 31, 2018 · In the last few decades, our understanding of Langerhans cells (LCs) has drastically changed based on novel findings regarding the developmental origin and biological …

Sep 23, 2022 · Langerhans cells are characterized by the presence of rod- or tennis-shaped cytoplasmic organelles called Birbeck granules. They are present in the skin and the mucosa, …

Jul 29, 2018 · Langerhans cells are the only professional antigen-presenting cells that reside in the epidermis under steady-state conditions. They were first described by Paul Langerhans in …