Tennessee and 15 states have reached a $7.4 billion settlement with the Sackler family and Purdue Pharma for their role in the opioid crisis, the largest of its kind in US history.

Purdue Pharma and its owners, the Sackler family, have reached a $7.4bn settlement with US states to resolve a long-running legal saga involving the pain medication Oxycontin and its role in fuelling the opioid epidemic in the country.

The Sackler family agreed to give up ownership of the company that manufactures the powerful opioid. A previous deal was rejected by the Supreme Court.