Expert Rev Clin Pharmacol. 2010;3(3):321-329. Despite a propensity to block hERG channel function, as determined by electrophysiology, for a limited number of compounds no cardiac arrhythmias have ...
Inherited mutations in the hERG channel gene, or drug-induced inhibition of channel function lead to inherited or acquired Long QT syndrome (LQTS) and the development of lethal cardiac arrhthymias. As ...
Inherited mutations in the hERG channel gene, or drug-induced inhibition of channel function lead to inherited or acquired Long QT syndrome (LQTS) and the development of lethal cardiac arrhthymias. As ...
Expert Rev Clin Pharmacol. 2010;3(3):321-329. Torsades de pointes (TdP) arrhythmia is a potentially life-threatening cardiac disorder that is often associated with a prolonged QT interval in the ...
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