Two patients with congenital generalized lipodystrophy type 1 due to a variant in AGPAT2 (c.589-2A→G) who had been receiving insulin and metreleptin were switched to tirzepatide and were ...
What is Cushing's syndrome? Cushing's syndrome is a hormonal disorder. It’s caused when you have high levels of the hormone cortisol over a long time. Cushing's syndrome is fairly rare. It most often ...
Mibavademab is under clinical development by Regeneron Pharmaceuticals and currently in Phase II for Acquired Generalized Lipodystrophy (Lawrence Syndrome). According to GlobalData, Phase II drugs for ...
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, ...
Aging is the progressive loss of organ and tissue function over time. Growing older is positively linked to cognitive and biological degeneration such as physical frailty, psychological impairment, ...
Vascular complications, though rare in classical EDS, can be life-threatening, and this necessitates one to look for vascular associations in non-vascular, such as classical, forms of EDS due to the ...
Adipocytes Are the Control Tower That Manages Adipose Tissue Immunity by Regulating Lipid Metabolism
Regulation of Adipose Immune Responses by Lipid Metabolites Figure 2 Relationship between Lipodystrophy and Adipose Tissue Inflammation. In adipocytes, lipid metabolism is well balanced by several ...
written by Ana Raisa Jatahy Santos, Sabrina Pinto Ferreira, Moacir Benazzi, Mara Capra, Helen Paula Apparicio Medeiros, Ana Luísa de Jesus, Mirella Hansen de Almeida, Larissa Bianca Paiva Cunha de Sá, ...
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