NEW YORK – Immuneering on Thursday said it signed a clinical supply agreement with Regeneron to obtain the anti-PD-1 therapy Libtayo (cemiplimab) for a Phase IIa trial testing Immuneering's MEK ...

Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers ...

Researchers at The Wistar Institute, led by Jessie Villanueva, Ph.D., have made significant strides in combating ...

Erasca is a biotech company focused on developing therapies for RAS/MAPK pathway-driven cancers with a strong financial ...

Naporafenib is Erasca’s main candidate, and it has Fast Track status for NRASm melanoma. See why I rate ERAS stock as a buy.

However, its role in melanoma tumor growth remains insufficiently explored. This study investigates the inductive effect of itraconazole on autophagy-mediated apoptosis in melanoma cells. Method: ...

Using an intracardiac melanoma metastasis mouse model and RNA sequencing, the team identified significant alterations in gene expression, particularly in ferroptosis-related pathways. A key ...

Using an intracardiac melanoma metastasis mouse model and RNA sequencing, the team identified significant alterations in gene expression, particularly in ferroptosis-related pathways. A key ...

Cytotoxic means toxic to cells. Some people may have chemotherapy as a treatment for advanced melanoma skin cancer. This means the cancer has spread from where it started to another part of the body.

it identifies germline variants using blood as a reference and its performance in detecting variants in key oncogenic pathways is comparably sensitive (Appendix Fig A1A). The cohort consisted of ...

1Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida. 2Cancer Biology PhD Program, University of South Florida, Tampa, Florida.