In general, rearrangements of heterochromatic regions, such as various translocations between the Y chromosome and acrocentric chromosomes, are found to have no clinical consequence, whereas those ...

In the most comprehensive global analysis of genetic diversity ever undertaken, an international team of scientists has found ...

New sequencing approach resolves the genetic complexity of a rare Mendelian conditionMENLO PARK, Calif., Jan. 29, 2025 (GLOBE NEWSWIRE) -- PacBio (NASDAQ: PACB), a leader in high-quality, long-read ...

In the most comprehensive global analysis of genetic diversity ever undertaken, an international team of scientists has found that the genetic diversity is being lost across the globe but that ...

A study of occupational status published in Nature Human Behavior identifies 106 genetic variants, the importance of the interplay of genetics and family environment, childhood educational and ...

Institute of Quantitative Biology, College of Life Sciences, and School of Physics, Zhejiang University, Hangzhou, Zhejiang 310058, China ...

Chromosomal translocations occur in leukemias, lymphomas, sarcomas and some epithelial tumors and some generate unique fusion proteins. These translocation products may provide tumor-specific ...

Chromosomes are tightly coiled structures in each of your cells that contain DNA, the code for all life. DNA is organized in segments on chromosomes called genes. Humans typically have 46 ...

One specific change they analyzed is the translocation of human PAR2 (pseudoautosomal region 2), a swapping of the tips of our X and Y chromosomes. This occurred relatively recently in primate ...

Some of the material related to Down's Syndrome. A digitised copy is held by the Wellcome Library as part of Codebreakers: Makers of Modern Genetics. Material restricted in accordance with Data ...

A population bottleneck approximately 900,000 years ago is thought to coincide with genomic rearrangements, the fusion of chromosome 2 and the translocation of the pseudoautosomal region 2 (PAR2).