are syntenic with regions on the long q arm of human chromosome 21. Using some genetic tricks, scientists have induced translocations involving these mouse chromosomes, producing mice that are ...

Genetic disorders—Down Syndrome ... Similarly, a fetus with Down Syndrome has three copies of chromosome 21, rather than two, but two copies of all of the other chromosomes.

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact ...

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease.

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don’t ...

Researchers say study represents a resource that could also help to dissect Y-gene functions in other tissues.