New research shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own. The study provides a better understanding of immune ...

CD4-positive T cells are a subtype of lymphocyte. They are MHC class II-restricted and are important mediators of adaptive immunity. These cells are involved in both the induction and the ...

One avenue for new vaccine development is mucosal vaccines. In theory, dosing the vaccine directly into the respiratory tract ...

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that ...

A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of pro-inflammatory T helper ...

More information: Ganesan Ramamoorthi et al, Antitumor CD4+ T helper 1 cells target and control the outgrowth of disseminated cancer cells, Cancer Immunology Research (2025). DOI: 10.1158/2326 ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

He studies how tumor-recognizing T cells — a type of immune cell — respond to these solid tumors, and how to improve those responses to help patients. One research focus is on CD4, or "helper" T cells ...