Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.

B-cell prolymphocytic leukemia (B-PLL) is a rare, aggressive type of leukemia that progresses rapidly. People with B-PLL typically have a less favorable outlook. However, new targeted treatments ...

In patients with RCC, exceptional response to immunotherapy may be related to clonal neoantigen-driven cytotoxic T-cell responses, among other factors.

the team detailed how sEVs were engineered to target a receptor called DR5 (death receptor 5), which is present on the surface of many tumor cells. Activating DR5 initiates a self-destruct process in ...

A recently published paper in Science China Life Sciences reports an interdisciplinary study utilizing single-cell sequencing data analysis to identify GPCRs involved in the regulation of adipogenesis ...

Institute of Physics and Materials Science, Department of Natural Sciences and Sustainable Ressources, BOKU University, Peter Jordan-Straß 82, 1190 Vienna, Austria ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from ... a mouse model of B-cell lymphoma called Eµ ...