Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

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Objective Combination therapy with rituximab and belimumab is a novel treatment strategy for severe SLE and lupus nephritis.

Presynaptic localization of Dop1R1 and Dop2R in Kenyon Cells and giant neurons ... Bidirectional modification of dopamine receptor expression in dopamine neurons. (A) Schematic diagram of the ...

S3). Immunohistochemical analysis showed a dense lymphocytic infiltration of the lamina propria positive for T-cell receptor (TCR) α, CD3, CD4, and granzyme B but which did not express TRBC1 ...

The pre-B-cell receptor (pre-BCR), which comprises two Igμ chains and two germline-encoded surrogate light chains (SLC) that are associated with the signalling subunits Igα and Igβ, is formed ...

A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.

Recognition of specific antigen through the B-cell receptor (BCR) stimulates the activation of B cells, which ultimately results in the production of high-affinity antibodies and the provision of ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from ... a mouse model of B-cell lymphoma called Eµ ...

A new publication from Opto-Electronic Advances; DOI 10.29026/oea.2025.240152, discusses how multi-photon bionic skin ...

B-cell prolymphocytic leukemia (B-PLL) is a rare, aggressive type of leukemia that progresses rapidly. People with B-PLL typically have a less favorable outlook. However, new targeted treatments ...