Researchers developed a technique to gain a deeper understanding of ribosome function and their cooperative behaviors.

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which ... ribosomal and small nuclear RNA (tRNA, rRNA, snRNAs) fold into unique structures ...

RTCB is required for the splicing of both tRNA and XBP1 mRNA, whereas the DDX1 enzymatic activity is specifically required for tRNA splicing in vivo. Snaebjornsson et al. explore a selective ...

mt-tRNA modifications are essential for their normal functions ... This result implies that there are may be other mechanisms independent of miRNA-mediated mRNA degradation. Interestingly, microRNAs ...

All three studies concluded that short spacings between RNAP and the ribosome, either directed by the mRNA or by adding a drug to halt RNAP ... with the ribosomal P-site (carrying the peptidyl-tRNA), ...

Shares in CureVac have plummeted after a German court ruled that a patent it holds on mRNA-based COVID-19 vaccines was invalid. The validity of the patent is at the heart of patent litigation ...

The trial compared Moderna's MRNA-4157/V940 vaccine given alongside Merck & Co's cancer immunotherapy Keytruda (pembrolizumab) to Keytruda alone in patients with the skin cancer melanoma.

Goldman Sachs believes that the new tariffs imposed by US President Donald Trump on Canada, Mexico, and China are likely to have a limited short-term impact on global oil and gas prices. As a result, ...

Making the world smarter, happier, and richer.

Finally, we will address safety and manufacturing aspects for CAR T cells and discuss mRNA technologies and automation concepts for ensuring the future availability of safe and efficient CAR T cell ...