Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques ...

Experimental data demonstrated that the lipid-lowering action of statins may partly explain beneficial effects of these drugs; the so called 'pleiotropic effects' of statins include inhibition of ...

This results in reduction of cholesterol synthesis, and increased LDL receptor expression on peripheral cells, thereby reducing the level of circulating LDL-C. Although their main mechanism of ...

Statin treatment may reduce cardiovascular risk in people with HIV not only by lowering cholesterol but also by reducing coronary plaque and inflammation, Professor Steven Grinspoon told the ...

The mechanism that underlies the increase in HDL-cholesterol levels during statin therapy is poorly understood; proposed mechanisms include the reduction of cholesteryl ester transfer protein ...

“These results underscore the complexity of assessing the role of statin in cancer therapy and highlight the need for further research to elucidate the potential mechanisms and interactions ...

The aim of this article is to summarize the current knowledge on the underlying mechanism(s) that affect(s) the cholesterol-lowering action of probiotics. The accepted mechanism responsible for ...