Researchers have identified chronic wasting disease (CWD) prions in raw, cooked, and cured meat from an infected elk in Texas, confirming the presence of the infectious CWD-causing agents in muscle ...
The treatment, which uses base editing to make a single-letter change in DNA, reduced levels of the disease-causing prion protein in the brain by as much as 60%. There is currently no cure for ...
Ending the spread of CWD appears unlikely because the prions, which cluster in the brain and nervous system, can be ...
Feraud Director of the Center for Alzheimer’s Disease Research, wins the 2025 Rainwater Prize for Innovative Early-Career ...
The treatment, which uses base editing to make a single-letter change in DNA, reduced levels of the disease-causing prion protein in the brain by as much as 60 percent. There is currently no cure ...
Researchers have gained valuable insight into the development of prion diseases of the brain. Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer's, Parkinson's ...
But in other cells, especially some neurons in the brain, a misfolded prion is a death sentence. As CWD prions accumulate throughout the host’s brain and spinal cord, the widening destruction of ...
Researchers at Ruhr University Bochum discovered that a lipid anchor on nerve cell membranes stabilizes prion protein folding, preventing harmful aggregation linked to prion diseases. Their in vitro ...
But in deer with CWD, diseased prions fold in abnormal shapes and accumulate throughout the animals' nervous system, including the brain — causing weight loss, an unsteady gait, diminished fear ...