Method to measure blood-brain barrier permeability accurately developed
For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the ...
Too Old to Operate1d
Sex Differences in Plasma LBP Levels in SIRS and Sepsis
The following is a summary of “Plasma Lipopolysaccharide-Binding Protein (LBP) Is Induced in Critically Ill Females with Gram ...
Opna Bio Receives Orphan Drug Designation for OPN-6602, an Oral EP300/CBP Bromodomain Inhibitor, for Multiple Myeloma
Opna Bio, a clinical-stage biopharmaceutical company focused on the discovery and development of novel oncology therapeutics, announced today that the FDA has granted orphan drug designation (ODD) to ...
Cryogenic electron microscopy uncovers key cellular recycling process for human health
A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling ...
AI-Designed Proteins – Unlike Any Found in Nature – Revolutionize Snakebite Treatment
Scientists have pioneered a groundbreaking method to combat snake venom using newly designed proteins, offering hope for more ...
Business Wire2d
LIB Therapeutics Announces FDA Acceptance of Biologics License Application for Lerodalcibep to Lower LDL-Cholesterol Across Broad Patient Population
LIB Therapeutics Inc. (LIB), a privately-held, late-stage biopharmaceutical company today announced the U.S. Food and Drug Administration (FDA) has ac ...
Monthly Prescribing Reference1d
Novel PCSK9 Inhibitor Lerodalcibep Under Review for Patients Requiring LDL-C Reduction
Lerodalcibep is an adnectin-based, small protein-binding, third generation proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor.
Phys.org9d
Cryogenic electron microscopy uncovers key cellular recycling process for human health
"Our study is a significant advance in understanding how proteins are recycled from endosomes back to the plasma (cell ... revealing a binding pocket on Retriever where this interaction happens.