Pathophysiologically, there is oxidative injury to DRG neurons early with persistence and some accentuation with increasing age. Oxidative DNA injury is associated with commitment to apoptosis as ...

Dorsal root ganglion is an entity of its own. Partial rhizotomy of the DRG is not intended to treat axial back pain, deafferantion pain or sympathetically maintained pain, such as complex regional ...

In their important manuscript, Costa et al. establish an in vitro model for dorsal root ganglion (DRG) axonal asymmetry, revealing that central and peripheral axon branches have distinct patterns of ...

Using this technique, they focused on neuron activity within the dorsal root ganglion (DRG). DRGs are located on both sides of each vertebra and act as a signal station, transmitting sensory ...

Methods and results: Expression of ASIC1a, 2, and 3 mRNA was found in vagal (nodose) and dorsal root ganglia (DRG), and was lost in mice lacking the respective genes. Recordings of different classes ...

The spinal cord has some cell clusters called the dorsal root ganglia (DRG). The axons of the neurons in these clusters are called sensory afferents. They enter tissues and sense various stimuli.

Antibodies against the intracellular domain of the fibroblast growth factor receptor 3 (FGFR3) possibly identify a subgroup of SN affecting mostly the dorsal root ganglion (DRG). The aim of this study ...

The hold was lifted in August 2021, following data from Novartis’ nonclinical toxicology study in non-human primates, which addressed questions around dorsal root ganglia (DRG) injury after ...

Indeed, it is this multifocality which often suggests the diagnosis of PND, as few other disorders in neurology have such a predilection for specific neurological locations such as the dorsal root ...

TL and LS dorsal root ganglia (DRG) were collected from healthy mice 3–10 days after retrograde tracing from the colon by Fast Blue (FB) injection using previously described methods.11 12 Individual ...

LONDON, Jan. 14, 2025 /PRNewswire/ -- Clarivate Plc (NYSE:CLVT), a leading global provider of transformative intelligence, today announced the launch of DRG Fusion, an innovative platform to ...