Frontiers4d
Radiation therapy attenuates lymphatic vessel repair by reducing VEGFR-3 signalling
Primary antibodies for detection of VEGFR-2 (clone 55B11 ... our platform of functional assays demonstrated a selective diminution of key LEC lymphangiogenic functions. Sprouting, branching, tube ...
Frontiers4d
Cell-Free DNA Promotes Thrombin Autolysis and Generation of Thrombin-Derived C-Terminal Fragments
Together, our results demonstrate the complex interplay between coagulation, NET formation, and thrombin cleavage and identify ... neutrophils were stained with Brilliant Violet 510 (BV510)-anti-CD45 ...
The EMBO Journal4d
Haploinsufficient phenotypes promote selection of PTEN and ARID1A-deficient clones in human colon
Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...
eLife1d
Spatial confinement induces reciprocating migration of epidermal keratinocytes and forms triphasic epithelia
In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...
eLife4d
Dissecting infant leukemia developmental origins with a hemogenic gastruloid model
This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...
Nature4d
A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation
You have full access to this article via your institution. This intrinsic property of AAV to undergo intermolecular concatamerization had shown great potential for expanding the current packaging ...