Antibodies, also known as immunoglobulins (IGs), are glycoproteins produced in response to an immune reaction and exhibit high specificity for the antigens that elicit the response. An antibody ...

Monoclonal antibodies (mAbs) may directly stall or kill tumour cells by binding tumour cell-specific antigens, or indirectly kill tumour cells by inhibiting the immune checkpoint molecules that ...

Indeed, most monoclonal antibody (mAb) drug discovery projects in I-O are focused on just a few targets, such as the checkpoint molecule programmed cell death 1 and CD19-specific chimeric antigen ...

Antibodies bind to specific antigens on pathogens. This means that only one type of antibody will bind to a matching antigen. For example, an antibody that can recognise an antigen on the ...