Individual genes express multiple mRNAs by pre-mRNA alternative splicing, alternative polyadenylation or use of alternative promoters (first exons). As a result, individual genes express multiple ...

How can only 25,000-30,000 protein-coding genes in humans produce the massive variety of proteins, cells, and tissues that exist in our bodies? The answer: alternative splicing. A critical finding ...

How can only 25,000-30,000 protein-coding genes in humans produce the massive variety of proteins, cells, and tissues that exist in our bodies? The answer: alternative splicing.

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

Christine Guthrie, a molecular geneticist whose studies of eukaryotic RNA yielded crucial insights into the workings of pre-mRNA splicing, the process by which introns are removed to produce mature ...

Further investigation into alternative splicing events showed how nematode infection modulates pre-mRNA splicing, affecting gene function and protein diversity. Validation using a transgenic hairy ...

We mapped hTERT enhancers and showed that transcriptional control does not fully account for the difference in hTERT mRNA levels between pluripotent ... regulation is primarily governed by alternative ...