Methods: Vials of meropenem were reconstituted with sterile water for injection and mixed with 0.9% sodium chloride injection (NS) to yield concentrations of 4, 10, and 20 mg/mL. Six replicate ...
Before injection into the HPLC system ... of the powder were mixed with 2.5 mL of 8.4% sodium bicarbonate in sterile water for irrigation. Two of the mixtures were adjusted to pH 0.1 and 12.9 ...