Proteins, the pillars of cellular function, often assemble into "complexes" to fulfill their functions. A study by the ...

Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...

The ribosome is a vital cellular machinery responsible for synthesizing proteins by translating messenger RNA (mRNA) sequences into polypeptide chains. This process, known as translation ...

Now the researchers have come closer to understanding how the ribosome works. "It is amazing that we can visualize the atomic details of the ribosome. Because they are tiny—around 20–30 ...

Although only a few rRNA molecules are present in each ribosome, these molecules make up about half of the ribosomal mass. The remaining mass consists of a number of proteins — nearly 60 in ...

Ribosomal translation is the process by which cells synthesize proteins based on the genetic instructions encoded in messenger RNA. It is essential for life, yet it is an incredibly complex process ...

The formation of protein complexes is a delicate process, with some proteins finding their match at synthesis.

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site ...

The rRNA molecules fold into complex secondary and tertiary structures, forming domains and motifs that are essential for ribosome function. The rRNA structures also provide binding sites for ...

In this valuable study, Roiuk et al employed a combination of ribosome profiling and reporter assays to provide convincing evidence that eIF2A is not involved in translational regulation in cultured ...

HIV-1, like other viruses, lacks the machinery to produce its own proteins and must rely on the host cell to translate its genetic instructions. After ...