That's because when you stub your toe, you're actually hitting a bundle of special nerve endings called nociceptors. They all fire at once, blaring a danger signal. But some signals travel faster ...

Studies indicate that nociceptors innervating the meninges and cerebral blood vessels are depolarized by CSD, and this depolarization of nociceptors is considered to be responsible for the pain ...

Medically reviewed by Gurdeep S. Sareen, PharmD Somatic pain and visceral pain are two distinct pain types that you'll ...