Southern Medical University scientists have reported the discovery and preclinical characterization of novel microtubule-inhibiting agents being developed for the treatment of cancer. Discovery of ...

The authors followed individual XMAP215 molecules during microtubule polymerization and measured a mean residence time of almost 4 seconds, during which time the microtubule grew by ∼0.2 μm ...

A single microtubule contains 10 to 15 protofilaments ... Microtubules are structures that can rapidly grow (via polymerization) or shrink (via depolymerization) in size, depending on how many ...

both mutant α-syn and LRRK2 are involved in the dynamics of actin and microtubule assembly. ER–Golgi transport: overexpression of LRRK2 may promote the improper polymerization of tubulin in ...