1,2 Ionization is critical for volatilizing sample analytes into a gas-phase. This primer covers a range of options which often require complementary equipment, such as syringe pumps, for efficient ...

Boston-based PerkinElmer Life and Analytical Sciences has released the prOTOF™ 2000, the first commercially available matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass ...

Of these, one very promising technique has already gained much interest in the research community: matrix-assisted laser desorption/ionization (MALDI) molecular imaging. For easy and successful ...

My research group at Drexel has focused on improving three broad areas in the analysis of biological and synthetic polymer systems using mass spectrometry: 1) understanding fundamentals of the ...

SELDI-TOF-MS can be considered as an extension of the matrix-assisted laser desorption/ionization (MALDI)-TOF-MS method. In both cases, proteins to be analyzed are cocrystallized with UV-absorbing ...

Single-cell MALDI mass spectrometry (MS) imaging resolution is currently limited by the size of laser spot diameter, matrix crystal size/homogeneity, displacement of analytes during matrix ...