A key component of this recognition process involves dendritic cell receptors, particularly C-type lectin receptors like DC-SIGN. These receptors bind to specific carbohydrate structures ...

These receptors initiate two arms of the immune ... mast cells, macrophages, and dendritic cells. These cells leave the bloodstream and take up residence in tissues throughout the body, where ...

Now, researchers from Osaka University have discovered that one receptor, called GPR31, is active in a specific type of ...

In addition to depositing in tissues and causing damage, these immune complexes can stimulate plasmacytoid dendritic cells via Toll-like receptors 7 and 9 to synthesize IFN-α. This cytokine ...

A recent study carried out by a research team from the Paul-Ehrlich-Institut investigated the immunomodulating properties of ...

Imiquimod is an active substance that activates the innate receptors TLR7/8 and used to treat basal ... use the body's own immune system to fight cancer cells. Plasmacytoid dendritic cells (pDCs), ...

Dendritic cells regulate both innate and adaptive immune ... manifested by downregulation of phagocytic receptors, and upregulation of Ag presentation machinery and costimulatory molecules.

Researchers at MedUni Vienna have developed a combination therapy using systemic interferon-I and topical imiquimod.