B-cell receptor-activation pathways following antigenic stimulation. BCR: B-cell receptor; BLNK: B-cell linker protein; BTK: Bruton's tyrosine kinase; DAG: Diacylglycerol; GSK: Glycogen synthase ...

Downstream of the pre-BCR, SYK (spleen tyrosine kinase) has a central role in the activation of pathways that regulate the proliferation and differentiation of pre-B cells. In the context of ...

Enhances B Cell Responses in Type 2 Inflammation Through IL-17RB Receptor,” published in the January 2025 issue of Allergy ...

Northwestern Medicine scientists have uncovered a key pathway controlling tumor growth in B-cell lymphomas, according to a ...

Together these proteins enable the host to recognize and clear pathogens and altered host cells. The complement proteins C3 and protease factor B have a central role in the activation pathways of ...

In patients with RCC, exceptional response to immunotherapy may be related to clonal neoantigen-driven cytotoxic T-cell ...