Figure 1: Oncogene Her2/neu-initiated, Akt-mediated p21 Cip1/WAF1 inactivation as a suppressor of tumour growth and the cell cycle.
"Based on transcriptome analysis and biochemical analyses, we found that ADM2 facilitates the expression of insulin-like growth factor 2 (IGF-II), which then triggers the activation of the AKT ...
It can slow down the growth of the cancer ... Capivasertib (Troqap) blocks certain types of AKT protein inside cells. It is used to treat some types of breast cancer where the cancer cells ...
Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA highlighting the role of exosomal RNA (exRNA) in head and neck cancers (HNCs).
Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy ...
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