The Office of the Attorney General came to a $7.4 billion settlement with the Sackler family and their company, Purdue Pharma, over their actions leading up to the opioid crisis, which has killed several hundreds of thousands of people in the last two decades.

Members of the Sackler family who own OxyContin maker Purdue Pharma, and the company itself, agreed to pay up to $7.4 billion to settle lawsuits over the toll of the powerful prescription painkiller.

The new settlement reopens a path to ending Purdue’s chapter 11 case, the longest and costliest corporate bankruptcy stemming from the U.S. opioid epidemic.